<br>The exception to the rule is the DOT1 household, members of which methylate K79 in the globular region of histone H3 and [Lawyers in My Area](http://git.2weisou.com/flordechaineux) that are structurally not related to SET-domain proteins 4 - 6 Current work means that SET-domain-containing proteins methylate just a few proteins in addition to histones (see later)
